Redox State of Glutathione and Cysteine in Plasma Following Acute Stroke Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Glutathione (GSH) ZELLX Free Radicals, Glutathione, Superoxide NADPH Oxidase N Acetylcysteine CGD MPO CCl4 Hexose Monophosphate Pathway or Pentose Phosphate Pathway Animations PharmaXChange.info