Frontiers Carnitine Traffic in Cells. Link With Cancer Comprehensive review of the expanding roles of the carnitine pool in metabolic physiology: beyond fatty acid oxidation Journal of Translational Medicine Springer Nature Link The role of carnitine in the transport of mitochondrial long chain Download Scientific Diagram Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine L carnitine is primarily synthesized in the liver from the amino acids lysine and methionine through a series of four enzymatic reactions, with the liver and kidneys converting the precursor butyrobetaine into active