Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Dihexa rescued the cognitive ability of APP PS1 mice. (A) Dihexa Download Scientific Diagram DIHEXA Alzheimer's Disease Puzzle: Delving into Pathogenesis Hypotheses The history of Alzheimers Disease